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The right way to Feed a Uncooked Fed Canine with EPI


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This weblog publish was initially printed in January 2017, it has been up to date with new info and republished after my canine was recognized with EPI (exocrine pancreatic insufficiency) in December 2019. Please needless to say I am not a veterinarian.  In case you are seeking to deal with your canine via weight-reduction plan for EPI or pancreatitis, please work with a pro-raw, holistic veterinarian.

In 2019, my canine was recognized with EPI (Exocrine Pancreatic Insufficiency).  Shit. Actually.

I realized about EPI a number of years in the past, and as I learn extra in regards to the situation and experiences shared by pet mother and father, I started to suppose that I lastly found out the supply of Rodrigo’s digestive points.  I introduced this as much as the veterinarian and was informed that Rodrigo didn’t have EPI.  This was based mostly on his regular blood work, not a particular take a look at.

Trying again, my vet could have been right.  Most instances of EPI develop earlier than a canine reaches his/her fourth birthday. And 70% of the instances of EPI are seen in German Shepherds, and 20% are seen in Tough-Coated Collies. Nevertheless, different canine can develop the situation, and older canine can develop EPI or pancreatitis.

Exocrine Pancreatic Insufficiency (EPI) in Canines

If a canine’s pancreas can’t produce sufficient digestive enzymes to interrupt down proteins, fat, and carbohydrates, the canine could develop EPI, which…

  • impacts a canine’s GI system,
  • disrupts the absorption of vitamins,
  • could result in weight reduction and persistent diarrhea,
  • and can finally result in hunger.

Signs of EPI in Canines

  • Continued weight reduction regardless of at all times being hungry
  • Pooping extra typically than the opposite canine; poop is bigger, yellow or grey in colour, and smooth
  • Canine eats his personal poop (coprophagia)
  • Elevated fuel and tummy noises
  • Occasional diarrhea and vomiting
  • Elevated anxiousness, fearful habits

My Canine has Exocrine Pancreatic Insufficiency (EPI)

In November 2019, after a couple of months of regular weight reduction, Rodrigo was examined once more. The outcomes of his blood work confirmed that one thing was up along with his pancreas. It wasn’t a transparent signal that we had been coping with pancreatitis, however the vet determined to check him for EPI given the blood work and signs (weight reduction, consistently hungry, unfastened stool, and diarrhea)

Accurage Blood Check for EPI

The Trypsin-Like Immunoreactivity is a blood take a look at most well-liked to fecal assessments as a result of the latter has confirmed to be inaccurate. In line with my veterinarian, “a canine or cat with EPI could have virtually no serum trypsin-like immunoreactivity within the bloodstream. The affected person have to be fasted for the take a look at to be correct, however solely a single blood pattern is required to make the prognosis. The feline model of this take a look at typically requires that the pattern be despatched to a college laboratory and customarily every week or so is required to get outcomes however the canine take a look at might be run in only a few days.”

On the left is the conventional abdomen. pancreas, and gut in a canine or cat stomach. On the proper is identical organs in a canine or cat who has exocrine pancreatic insufficiency. Discover the atrophied pancreas.

Did My Canine Have Low-Grade Pancreatitis?

I suspected that Rodrigo had EPI, however he examined adverse. What modified?

Our veterinarian defined that the most typical explanation for digestive enzyme deficiency is pancreatic acinar atrophy, the place the pancreas turns into shriveled and ineffective (see picture above). Whereas we normally see the indicators of EPI earlier than a canine reaches 4 years of age, the onset of EPI can occur if a canine is subjected to persistent pancreatitis that has destroyed over 90% of the functioning acinar glands. This was hinted at in his full blood panel outcomes; the EPI take a look at confirmed his situation.

One other explanation for EPI in canine is most cancers of the pancreas. Nevertheless, that is uncommon, and it is not the case with my canine.

Pancreatitis develops when a canine’s pancreas is infected and never working appropriately.  It is seen in chubby canine, older canine, and canine fed a high-fat weight-reduction plan.  I solely noticed a few the signs listed under in Rodrigo, and I believed it was simply his digestive points performing up. Possibly all this time, he was going via durations of pancreatitis.

Signs of pancreatitis, in response to PetMD, embody:

  • Fever
  • Vomiting
  • Diarrhea
  • Lack of urge for food (anorexia)
  • Weight reduction (extra widespread in cats)
  • Dehydration
  • Fatigue and sluggishness
  • Delicate to extreme belly ache (could change into extra extreme after consuming)
  • Melancholy
  • Elevated coronary heart fee
  • Issue respiration

The one signs Rodrigo exhibited had been occasional diarrhea and weight reduction. The diarrhea was attributed to his digestive points, which he is had his complete life. And the load loss might be attributed to a slight lower in meal measurement and a rise in train.

Greatest Eating regimen for Canines with EPI

In fact, I am biased, so I will say a uncooked weight-reduction plan is finest for canine with EPI. As soon as we acquired this prognosis, I used to be relieved that I used to be already feeding recent meals and questioned how a lot of my canine’s present weight-reduction plan contributed to him going so lengthy with out growing full-blown EPI.

I imagine {that a} uncooked weight-reduction plan is finest as a result of it is simpler to digest, and the vitamins are available for absorption. However uncooked is not the remedy for EPI. Since my canine’s pancreas is not offering the required enzymes, I would like so as to add them to Rodrigo’s weight-reduction plan as meals (pancreas) or dietary supplements.

Advantages of Beef Pancreas for Canines

As a uncooked feeder, I desire to feed my canine entire meals as an alternative of dietary supplements after I can, so the primary thought for me can be so as to add recent pancreas to Rodrigo’s weight-reduction plan to complement what he misplaced via EPI.

The pancreas is a glandular organ within the digestive system and endocrine system of vertebrates. The pancreas is concerned in blood sugar management and metabolism throughout the physique, and likewise within the secretion of drugs which assist digestion. The pancreas performs a significant position within the digestive system (which captured my consideration). It secretes a fluid that comprises enzymes into the duodenum. These enzymes assist to interrupt down carbohydrates (normally starch), proteins and lipids (fat).

Supply: Wikipedia

In my analysis on uncooked feeding, I noticed pancreas listed as helpful to canine as a result of…

  • it is a part of a balanced uncooked meals weight-reduction plan (pancreas is offal),
  • it may be used medicinally for canine which have EPI (Exocrine Pancreatic Insufficiency) or pancreatitis,
  • it is nice for digestion.

Learn 3 Things You Need to Oknow When Feeding Pancreas

Feeding Pancreas Medicinally to Canines

Please needless to say I am not a veterinarian.  In case you are seeking to deal with your canine via weight-reduction plan for EPI or pancreatitis, please work with a pro-raw, holistic veterinarian.

Serving Quantity of Pancreas for Canines

I reached out to my supply of pancreas and was informed to feed 2 ounces of uncooked beef pancreas twice every day for each 20lbs of physique weight.  Feeding greater than 2 ounces twice every day is not really useful.

To maximise enzyme effectivity, we’re suggested to whip the pancreas with a fork or wire whisk to a pudding-like consistency or liquefy in a blender and serve at room temperature. And it is essential to do not forget that pancreas has a shelf lifetime of solely three months.

I selected to not feed uncooked pancreas as a result of I haven’t got a constant supply and a complement is less complicated to make use of.

Pancreas Dietary supplements for Canines

My veterinarian really useful a number of dietary supplements and approves the 2 I’ve tried with Rodrigo. Bio Case Plus is a powder complement made from porcine pancreas, containing B12 (intrinsic issue to assist absorption) as many canine recognized with EPI are additionally vitamin B poor. I later switched to Enzyme Diane’s Pancreatin 8x, which comprises Protease (protein), Amylase (starch/greens), and Lipase (fats).

The Enzyme Diane complement would not include cellulase, an enzyme our canine can’t produce. Cellulase helps to interrupt down the mobile wall of greens, which makes the vitamins extra bioavailable. Though our canine do produce amylase, it is not in excessive quantities. Subsequently, I break the mobile wall of greens in my meal prep via pureeing, blanching, or freezing.

USING DIGESTIVE ENZYMES: Combine the powder into my canine’s meals, permit it to germinate for 15-20 minutes (to start predigesting the meals), after which feed my canine.  This complement gives enzymes to assist my canine digest meals and take in vitamins.

PREMIXING MEALS WITH ENZYMES: Some complement manufacturers advise in opposition to premixing batches of meals with enzymes. With Enzyme Diane, I can premix as much as 4 days of meals for my canine.


In case your canine has been recognized with EPI, ship the hyperlink to Enzyme Diane’s for assessment. They could advocate a barely totally different product than what I give to my canine. Additionally, in case you have pet insurance coverage, contact them to search out out if the complement will probably be partially coated.


Extra Dietary supplements for Canines with EPI

Different dietary supplements really useful by our veterinarian and by pet mother and father elevating canine with EPI are:

Useful Sources for Canines with EPI

The sources that I’ve discovered most useful embody:

  • Uncooked Feeding Group: EPI – K9EPIGlobal – this group has a whole lot of members who’re uncooked feeders.
  • Enzyme Diane: This web site comprises details about EPI for canine, success tales to offer us hope, and a complement that folks rave about.
  • EPI4Dogs Basis: that is one other web site that has a whole lot of nice info to assist us find out about elevating canine with EPI.

My Questions About Feeding Uncooked to a Canine with EPI

1 – Do I’ve to make use of the complement with each meal? – Sure. Rodrigo will not be capable to digest his meals with out utilizing the complement. The complement would not final a full day in his system. As an alternative, it pre-digests his meals, permitting him to soak up the vitamins.

2 – Ought to I take advantage of the complement when feeding uncooked meaty bones? – Sure. I used to be suggested to combine up a small quantity of floor uncooked with the complement and feed it to Rodrigo half-hour earlier than giving the canine their bones. If I am feeding leisure bones or chews to my canine to wash their enamel and fulfill their chew drive, then the complement is not mandatory.

3 – Can I premake meals with the complement, saving time at mealtime? – It is dependent upon the complement. Some complement manufacturers advise in opposition to premaking meals with enzymes as their complement would not work effectively beneath these situations because it continues to interrupt down the meals, even when saved within the fridge. With Enzyme Diane dietary supplements, I can combine as much as 4 days of meals, making it simpler for others to feed my canine.

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